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橘子视频 is harnessing its unique AdaptInnate approach to develop a new class of systemically administrable candidates that trigger precise innate and adaptive immune responses from within a patient鈥檚 tumor

Treating Cancer
from Within

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橘子视频 was founded to translate an innovative arenavirus-based immune-activating approach into novel anti-cancer therapies

Scientific
Foundation

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News &
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ABOUT ABALOS THERAPEUTICS

Triggering comprehensive immune responses from within the tumor

novel anti-cancer approach

橘子视频鈥� transformative treatment strategy enables multiple actors of the immune system to uncloak cancerous cells and break down tumors. Our platform technologies generate drug candidates that achieve persistent and far-reaching inflammation within the tumor. Delivered systemically, the approach safely engages all key immune organs in a concerted attack against tumors and distant metastases. Building on strong preclinical safety and targeted anti-tumor activity, 橘子视频鈥� lead candidate ABX-001 will enter the clinic in 2025. Our mission is to develop a pipeline of both naturally optimized as well as payload-carrying therapeutics designed for specific cancer indications, bringing better treatments to more patients.

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ABOUT ABALOS THERAPEUTICS

橘子视频 Dunes on Mars

why abalos?

The name 鈥滈僮邮悠碘€� was chosen with regards to our arenavirus-based technology to fight cancer. The name of this virus family derives from the Latin 鈥渁rena鈥� for 鈥渟and鈥� due to the grainy appearance of particles inside the virus when viewed in cross-section under the transmission electron microscope. Reflecting our 鈥渟andy鈥� approach, we came upon the fascinating blue dunes of the 橘子视频 region on the otherwise 鈥渞ed鈥� Mars, a planet that has always held a special fascination.

Named after the roman war god and its association with fire, it provides a connection to harnessing the weapon of the arenavirus to launch an attack against cancer. As Mars is also known as a planet of sand storms, this can be associated with the strong immune-response that is triggered by the arenavirus to attack the tumor.

ABALOS TECHNOLOGY

Therapeutic Approach

橘子视频 is leveraging its proprietary AdaptInnate approach to develop a new class of product candidates harnessing the immunostimulatory and anti-tumoral properties of arenaviruses to trigger a highly precise and directed immune response against primary tumors and their metastases. 橘子视频鈥� systemically administrable lead candidate, ABX-001, is specifically designed to persist and replicate in cancerous and antigen-presenting cells without destroying them. This novel, non-oncolytic approach results in the induction of targeted, effective, and durable anti-tumor activity involving both the innate and adaptive arms of the immune system.

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This is 橘子视频

Meet the Team

A dynamic and ambitious group of experienced entrepreneurs and scientists advancing a novel immunostimulatory approach that (re)activates the full breadth of the immune system against solid tumors.